1. All cases with Blood Coagulation Failure
2. Bleeding Organs
4. Ozone Allergy
5. Hemorrhagic or Apoplectic Stroke
6. Ozone Intolerance
Ozone in low concentrations is known to produce a moderate hypo-coagulation effect, so all the drugs decreasing blood coagulation (anticoagulants, aspirin, etc.) are to be discontinued during the course of ozone therapy. In women the treatment course is to be broken up for menstrual periods.