Ozone and Rectal Insufflation
Dr. Velio Bocci, the world’s leading expert on ozone therapy, said about rectal ozone, “… (ozone) can re-equilibrate the bacterial flora (as) anecdotal results suggest a beneficial effect.”
“Another commonly used form of administration is rectal insufflation. Essentially, a catheter is put into the colon and gas from an ozone machine is allowed in at a determined concentration and flow rate. The ozone can also be self-administered this way with a Teflon bag.8 One study, by Knoch, Roschke, and Klug, reveals how the method works. After oxygen-ozone mixtures are absorbed through the wall of the large intestine, they enter the bloodstream and result in a PaO2 increase within the entire organism, raising PaO2 almost 100 percent higher than oxygen alone would, and having no adverse effects.(9)
Dr. Beyerle, who is certified by the German Medical Ozone Society, studied the rectal insufflation method of delivering ozone therapy in Germany with one of the pioneers in the field, Dr. Rilling Beyerle explains that “the blood vessels in the colon, small intestine, and bladder are the mesenteric veins, which deposit into the portal vein and go straight to the liver. The simple introduction of the catheter into the colon, at a low flow rate to increase concentration, gets ozone into the systemic venous system. Dr. Rilling says that if nothing else is done but rectal insufflation, which does not really require a physician at all, you see dramatic results.”(3)
Positive therapeutic effects on diseases of the rectum and colon have been noted with this method since 1936. Beyerle has seen people recover from irritable bowel syndrome, colitis, and Crohn’s disease, almost immediately. “There may be some initial discomfort, some bloating and gas on occasion, but as far as irritations, we have yet to see any contraindications. If you’ve got colitis or irritable bowel syndrome, when ozone is administered properly, there are no negative side effects, only positive ones. It renews the mucous lining and gets to the bacterial infestation that has infiltrated the tissues of the colon.”(3)”
A Different Source With Similar Comments
In Chapter 9, we will briefly examine the pathogenesis of the diseases where RI is best employed, but here it may be useful to speculate about the local effects of ozone. These may be as follows:
(a) Biochemical effects. In the studies already cited (León et al., 1998; Barber et al.,1999; Peralta et al., 1999, 2000; Borrego et al., 2004; Gonzalez et al., 2004), RI in rats upgraded the enzymatic antioxidant response in liver and kidney but the viability of enterocytes (intestinal absorptive cells) was not examined.
(b) Bactericidal effects.. The human colon-rectum contains up to 600 g of about 400 species of mostly anaerobic bacteria, and ozone may partly change the environment for a short while. … bactericidal activity per se is probably unimportant ….
Particularly in the last paper, it was postulated that the somewhat neglected gut flora has a crucial immunostimulatory role. This idea remains valid today and it is possible that Rectal Insufflation favors a slight increase of lipopolysaccharide absorption with the consequence of enhanced activation of intrahepatic lymphocytes, Ito’s and Kupffer’s cells (O’Farrelly and Crispe, 1999), which may change the evolution of chronic hepatitis.
(c) Modification of the bacterial flora equilibrium. Owing to the multiplicity of bacterial species, this remains a complex area….. The bacteria and their products interact with each other and with the enterocytes (intestinal absorptive cells), goblet and enteroendocrine cells (producing a myriad of hormones) and the gut-associated lymphoid tissue, GALT (Hooper and Gordon, 2001).
On the other hand, it is well known that contaminated food, water and antibiotics can subvert this dynamic symbiosis by allowing the establishment of pathological bacteria and fungi like Candida albicans, C. tropicalis, Torulopsis glabrata, etc. The successive dysmicrobism (upset microbiome) usually has far-reaching deleterious consequences, ranging from transient to chronic enterocolitis and to autoimmune reactions and therefore we must try to correct it in order to restore normal homeostasis. Whether Rectal Insufflation with a daily input of oxygen-ozone can re-equilibrate the bacterial flora and lead to normal immunoreactivity remains to be demonstrated (and explained), although anecdotal results suggest a beneficial effect.
The goal of the study, which lasted a total of 90 days, was to verify the effects induced by ozonated water and rectal insufflation on the overall well being of 34 individuals affected by intestinal dysbiosis.
The authors show how the mixture of O2-O3 represents a valid aid for the restoration of the physiological status of the altered mucosa, thus ensuring the digestive and detoxifying functions of the gastrointestinal tract: https://www.pagepressjournals.org/index.php/ozone/article/view/7304/7100.
“All individuals presented a significant improvement, already by the first assessment, which became considerably more significant, from a statistical point of view, by the end of the study.”