Ozone Therapy for Biohacking and Performance Enhancement

Uses, Benefits, Safety, and How to Do It
Table of Contents

You may want to live to your physical potential.

What does that mean?

It asks questions like:

  • How can I have the highest mental capacity and clarity?
  • How can I avoid diseases?
  • How can I stay pain free into old age?
  • How can I retain a youthful, attractive look?
  • How can I stay physically fit and active?

You want to be unstoppable and crush goals, both in career and personal aspects.  You want to slow and prevent aging, to create a youthful, fit, and attractive body.  

In this article, we will cover:

  • Benefits of ozone therapy: increases energy, modulates immune function, increases stamina, decreases recovery time, reduces pain/inflammation, and reduces brain fog
  • Safety of ozone therapy: ozone therapy has an adverse event rate lower than the use of aspirin
  • Best ways to apply ozone therapy: IV in the clinic or rectal insufflation at home
  • How to apply ozone therapy at home


Ozone therapy benefits

Ozone therapy works synergistically with the body by stimulating it on a fundamental level.  It works by stimulating the NRF2 pathway via mild acute oxidative stress.  In turn, this assists in:

  • Increases energy
  • Modulates the immune system
  • Increases stamina (tiring out less quickly)
  • Decreases recovery time
  • Reduces pain and inflammation
  • Reduced brain fog/enhanced mental clarity

Dr. Troy Baker improved his Iron Man by 40 minutes after 6 weeks of ozone therapy.

Increases energy and stamina

Oxygen is the forgotten nutrient.  It’s the most important nutrient.  No other nutrient is as necessary to our livelihood. 
The big difference between a 20 year old and a 70 year old is how well they utilize oxygen and create energy.  

Oxygen essentially has two pathways when it enters the body: creates energy or damages cells. (1, 2, 3)

There is a robust scientific community around ozone therapy.  Within the literature, you find ozone therapy to be versatile and causes a “cascade” effect of positive reactions. They also claim it increases oxygen efficiency and stimulates the body to create more energy.  (4, 5, 6, 7, 8)

Oxygen efficiency is different from breathing oxygen. Breathing gets oxygen into your body, but oxygen efficiency describes how well you use it.

You can breathe all the oxygen you want (not a bad idea), but how well your body puts that oxygen to use (oxygen efficiency) is vital.  Ozone therapy may help people increase their oxygen efficiency.

So if you improve oxygen efficiency, you essentially improve all body systems.  This is why it’s helpful for increasing energy, cognition, metabolism, and recovery.

This is the miracle of your body, not ozone.  Ozone is just the stimulus to get your body to operate efficiently.  

Dr. Bocci, the Father of Ozone Therapy, wrote about ozone therapy improving oxygen utilization when he says,

“It must be added that ozonated erythrocytes show an improved glycolysis with an increase of ATP… Extensive data have been reported in reviews and two books. It is now clear that a “physiological” ozone dose … triggers an acute and precisely calculated oxidative stress able to activate several biological processes…”

Hyperbaric oxygen has a similar effect, albeit somewhat different and useful in different scenarios (such as brain injuries).  Ozone therapy is much more practical, less expensive, and easy.

Modulates the immune system

A modulated immune system is better at fighting disease than any drug.  

But if your immune system is overactive, as is the case with autoimmune diseases, PENDING ozone brings the immune system down to appropriate levels. 

On the other hand, if your immune system is underperforming, like it does with mold toxicity, lyme disease, etc, ozone gives your immune system a boost. (23, 24, 25, 26, 27)

Ozone provides the stimulus for your immune system to balance and function appropriately.

(An autoimmune disease, before and after ozone therapy by Dr. Rowen)

Safety of Ozone Therapy

There are millions of ozone therapy treatments done every year, both by home-users and over 60,000 doctors worldwide.

Done appropriately, ozone therapy is a safe application.

An adverse event report was published showing a lower adverse event rate than aspirin.

However, ozone cannot be breathed directly into the lungs.  There are no antioxidant defenses in the lungs.  Other parts of the body (blood, vagina, rectum, etc.) have an antioxidant defense system that interacts directly with the ozone and causes a cascade effect, leading to the benefits.

Best Way to Apply Ozone Therapy for Athletic Performance

Intravenous or rectal ozone therapy are the best routes to elicit systemic benefits.

Here is a comparison of the two options:

How People Do Ozone Therapy

For less money, people do ozone therapy at home on a daily basis in five minutes or less.  Many reports claim that rectal insufflation is 50 - 95% as effective as the intravenous methods.  Rectal insufflation has a couple other advantages:

  • It can be 5x per week - more ozone therapy!
  • It can be done at home
  • For the price of a few intravenous therapies at the doctor’s, people get their own equipment at home

Total cost for a basic home set up is under $1,500 after all is said and done.  


Four steps are involved…

STEP 1: Download the Guide

STEP 2: Get An Oxygen Tank

STEP 2: Buy An Ozone Generator complete Kit

STEP 3: Enjoy the Benefits of Ozone Therapy at Home

We have articles to compare equipment and find exactly.  You can also find details on how to do everything.


Ozone therapy is a viable tool for enhancing the body because it increases oxygen efficiency, modulates the immune system, improves blood flow, and mediates oxidative stress.  I.e. More energy, better recovery, more stamina, and less down time.

Of course, the foundation of health is paramount - good nutrition, water, air, and exercise.  But ozone therapy can serve as a tremendous add on to optimize the body.

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